logesanRecommended gestational age (GA) for vaccination in pregnancy differs by vaccine and, for RSV and influenza, may also depend on seasonality. The table below summarizes typical guidance (US/ACIP–ACOG–aligned) for uncomplicated pregnancies. We urge vaccinators to always adhere to national guidelines, product information, local RSV/flu season, and individual risk.
| Vaccine | Main purpose in pregnancy | Recommended GA interval (weeks) | Notes |
|---|---|---|---|
| Tdap | Protect newborn against pertussis via maternal antibodies | 27–36 weeks’ gestation in every pregnancy; preferably early in this window | One dose in each pregnancy, regardless of prior Tdap history; aim for 28–32 weeks if possible to maximize antibody transfer before term birth. |
| Inactivated influenza (seasonal flu) | Protect mother and infant in first 6 months | Any trimester if pregnant during flu season; often given from 2nd trimester, but can be 1st–3rd trimester as needed | ACIP/ACOG: vaccinate at any time in pregnancy when vaccine is available and flu is circulating; some data suggest higher infant protection if given in 3rd trimester, but do not delay if season has started. |
| Maternal RSV vaccine (Abrysvo) | Protect infant from severe RSV in first months | 32+0 to 36+6 weeks’ gestation, for seasonal protection of infant | Single dose in eligible pregnancies during local RSV season; not given ≥37 weeks because there is insufficient time for antibody development and transfer; earlier in the 32–36 week window may optimize transfer. |
| COVID-19 (mRNA / updated vaccine) | Protect mother from severe COVID-19 and provide infant antibodies | Any trimester; as soon as vaccine is available / indicated | ACOG and CDC: vaccinate in any trimester, with emphasis on earliest feasible timing to reduce maternal risk; boosters also in any trimester when due. |
To view the full table – click and download the PDF file.
By Health Literacy Asia
Health Literacy Asia
